Glycemic Status, Lipid Profile and Proteinuria in Diabetic nephropathy

Glycemic Status, Lipid Profile and Proteinuria in Diabetic nephropathy

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INTRODUCTION: Diabetic nephropathy is one of the major complications of Diabetes Mellitus characterized by persistent albuminuria, elevated arterial blood pressure, a relentless decline in glomerular filtration rate (GFR) and a high risk of cardiovascular morbidity and mortality.METHODS: In this study, urinary micro-albumin estimation was done in 177 diabetic patients.This study aims to ascertain association of glycemicstatus, lipid profile Outdoor Round Cocktail Table and proteinuria in Type 2 Diabetes Mellitus with nephropathy.

RESULTS: Among 177 patients, 26 had frank proteinuria, 79 had micro-albuminuria and 72 were without proteinuria.Increased frequency ofproteinuria was seen in male than female.Micro-albuminuria and frank proteinuria was seen more in older age group.

The multiple comparisons showed the significantly increased levels BAR 88% INTENSELY DARK of urea, creatinine, fasting blood glucose in micro-albuminuria and overt proteinuria patients in comparison to without proteinuria.Glycated hemoglobin level was increased with the increasing age group particularly in overt proteinuric patients.CONCLUSIONS: The glycemic control, monitoring of lipid profile and early urinary protein estimation with better management may delay diabetic nephropathy or its further complications in diabetes mellitus.

KEYWORDS: diabetes mellitus, diabetic nephropathy, frank proteinuria, glycated hemoglobin, micro-albuminuria.